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The Exchange Daily - December 2, 2025

Today’s Show Notes: Genesis Mission’s first AI RFI, enterprise reinvention, AWS–Google multicloud, FDA agentic AI, Android zero-days, and data centers in space.

NNSA kicks off Genesis Mission with a national security AI RFI

The Genesis Mission is moving from executive order to execution. The Department of Energy’s National Nuclear Security Administration has issued a Request for Information titled “Transformational AI Capabilities for National Security,” just days after the order was signed. The RFI asks industry, labs, and academia to propose ways to use AI across nuclear security missions, from modeling and simulation to threat detection and secure data management.

For technology and security leaders around the federal space, this is an early blueprint for how classified AI environments will be shaped. It puts data curation, model hosting, and cyber controls at the center of the conversation and signals that agencies will expect partners to arrive with robust architectures and governance already in place.

Sources:
https://www.energy.gov/nnsa/articles/nnsa-demonstrates-swift-action-genesis-mission


OpenAI and Accenture launch a flagship enterprise AI reinvention program

OpenAI and Accenture are deepening their relationship with a new collaboration that makes OpenAI a primary AI partner for Accenture’s next generation of services. Accenture plans to equip tens of thousands of professionals with ChatGPT Enterprise access and OpenAI certifications while the two firms co-design a flagship program to embed agentic AI in production workflows.

For CIOs, CTOs, and heads of transformation, this partnership matters because it changes how enterprise AI shows up in your organization. You will increasingly see integrator teams arrive with opinionated patterns for AI-driven finance, supply chain, and customer operations. The opportunity is real acceleration; the risk is ceding too much architectural control unless your own teams stay close to design, data, and risk decisions.

Sources:
https://www.businesswire.com/news/home/20251201836413/en/OpenAI-and-Accenture-Accelerate-Enterprise-Reinvention-with-Advanced-AI
https://finance.yahoo.com/news/openai-accenture-accelerate-enterprise-reinvention-125900838.html


AWS re:Invent 2025 doubles down on agentic AI and multicloud networking

Day one of AWS re:Invent 2025 is heavy on agentic AI and connectivity. AWS is promoting services like AWS Transform for modernizing legacy code and applications, along with new agentic capabilities in Amazon Connect that can orchestrate more autonomous customer interactions. At the same time, AWS and Google Cloud have announced a jointly engineered private interconnect aimed at simplifying high-bandwidth multicloud connectivity.

The strategic message is that AI and multicloud are converging at the network layer. Enterprises that have treated multicloud as opportunistic will now be pushed toward more deliberate architectures, while security and compliance teams will need to treat identity, logging, and policy as cross-cloud concerns. The upside is more flexibility; the downside is that misconfigurations in one cloud can now ripple more easily into another if you are not careful.

Sources:
https://www.aboutamazon.com/news/aws/aws-re-invent-2025-ai-news-updates
https://siliconangle.com/2025/12/02/aws-google-cloud-partner-faster-multicloud-connectivity/
https://www.techradar.com/pro/aws-thinks-it-has-the-answer-to-your-multi-cloud-interoperability-issues


FDA deploys an agentic AI platform for staff to streamline regulatory work

The Food and Drug Administration has announced an agency-wide deployment of an agentic AI platform designed to help staff with complex, multi-step tasks. The tools can assist with pre-market reviews, post-market surveillance, inspection planning, compliance checks, and administrative work, all within a secure government cloud environment and under human oversight.

For leaders in life sciences, healthcare, and other regulated industries, this is a crucial signal. Regulators are not just supervising AI, they are using it. That means expectations around documentation, validation, and governance for AI-assisted workflows will continue to rise. It also gives compliance and IT teams a reference point for how AI can be rolled out with guardrails inside a complex, risk-sensitive organization.

Sources:
https://www.qualityassurancemag.com/news/fda-deploys-agentic-ai-for-all-agency-employees/
https://www.investing.com/news/economy-news/fda-deploys-agentic-ai-capabilities-to-enhance-staff-workflows-93CH-4384444
https://pharmaphorum.com/news/fda-doubles-down-its-push-ai
https://tobaccoreporter.com/2025/12/01/fda-deploys-agentic-ai-to-assist-regulatory-reviews/


Android December 2025 update fixes 107 flaws and two active zero-days

Google’s December 2025 Android Security Bulletin lands with one hundred and seven vulnerabilities patched across the platform. Two high-severity flaws in the Framework component are already being exploited in targeted attacks, and related fixes roll into the December Wear OS bulletin as well. The bulletin notes that devices with the 2025-12-05 patch level or later will have these issues addressed.

For enterprise mobility teams, this is an immediate action item. Android phones and tablets now sit at the center of multifactor authentication, executive communications, and frontline workflows. Leaving devices unpatched increases both compromise risk and the likelihood that attackers can pivot into more sensitive systems. A structured rollout plan, starting with high-risk users and regions, should be on every CISO’s list this week.

Sources:
https://source.android.com/docs/security/bulletin/2025-12-01
https://www.securityweek.com/androids-december-2025-updates-patch-two-zero-days/
https://www.malwarebytes.com/blog/news/2025/12/google-patches-107-android-flaws


Project Suncatcher and the long-term future of AI data centers

Google has gone public with Project Suncatcher, a research effort to explore placing AI data center infrastructure in space. The concept involves solar-powered satellite constellations equipped with Tensor Processing Units and high-speed optical links, with the goal of running machine-learning workloads off-planet to ease pressure on Earth’s power and water resources.

For CIOs and infrastructure leaders, this is not tomorrow’s procurement, but it is tomorrow’s context. AI demand is straining terrestrial grids, driving community pushback against new data centers and raising ESG questions. Suncatcher and similar ideas suggest that long-term infrastructure planning will have to account for power constraints, regulatory pressure, and a future in which “where your compute lives” may include orbits as well as regions.

Sources:
https://research.google/blog/exploring-a-space-based-scalable-ai-infrastructure-system-design/
https://www.businessinsider.com/google-project-suncatcher-sundar-pichai-data-centers-space-solar-2027-2025-11
https://www.businessinsider.com/data-centers-in-space-google-moonshot-project-suncatcher-tesla-openai-2025-11


Topics We’re Tracking (But Didn’t Make the Cut)

Dropped Topic: Agentic AI as an attack amplifier for poor cyber hygiene

  • Why It Didn’t Make the Cut: Important but overlapped with earlier coverage and would have pushed today’s mix too far toward cyber risk.

  • Why It Caught Our Eye: Reinforces that attacker AI will scale existing weaknesses, not just exploit new model-specific flaws.

Dropped Topic: OpenVPN vulnerabilities affecting enterprise VPN deployments

  • Why It Didn’t Make the Cut: Strong technical advisory, but similar patch stories appear today and Android was higher-impact for most enterprises.

  • Why It Caught Our Eye: OpenVPN underpins many commercial and in-house VPNs, making it a good reminder to inventory and patch dependencies.

Dropped Topic: Kubernetes Portworx SSRF flaw in kube-controller-manager

  • Why It Didn’t Make the Cut: Narrower impact and audience; we prioritized broader stories relevant to more cloud-native shops.

  • Why It Caught Our Eye: Another example of “cluster plumbing” creating data-exfiltration paths from the control plane.

Dropped Topic: Industry push for unified federal cybersecurity requirements

  • Why It Didn’t Make the Cut: Policy conversation is still early, and the proposals have not yet translated into concrete rules.

  • Why It Caught Our Eye: A unified framework could materially reshape how large enterprises manage overlapping sectoral regulations.


This update was assembled using a mix of human editorial judgment, public records, and reputable national and sector-specific news sources, with help from artificial intelligence tools to summarize and organize information. All information is drawn from publicly available sources listed above. Every effort is made to keep details accurate as of publication time, but readers should always confirm time-sensitive items such as policy changes, budget figures, and timelines with official documents and briefings.


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